---
title: "Homepage"
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date_modified: 2026-09-24
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# DECODING KIDNEY DATA For Smart Fluid Management

FIZE Medical closes the gap in fluid management with real time clinical
intelligence, supporting early intervention and better patient outcomes.

[Let's Connect](https://fizemedical.com/demo/)

## Fluid Management: The Most Intricate Challenge in Critical Care

Physicians face multiple challenges in managing fluids in critically ill patients: Fragmented information from different sources, urine-output data essential for guiding patients toward optimal fluid balance is not available in real time, and the manually recorded UO data is prone to inaccuracies[1] and is not streamlined in the EMR.

[Learn More](https://fizemedical.com/article/optimizing-fluid-management-in-critically-ill-patients-the-role-of-continuous-urine-output-monitoring/)

## Fluid Mismanagement Implications

Inadequate fluid management can result in fluid overload or hypovolemia, increasing morbidity and mortality. Beyond the clinical impact, fluid mismanagement represents a significant economic burden, amounting to billions of dollars annually in the US alone.\*

#### 300,000[2]

Patients die of AKI per year in the US alone

#### $10 billion[4]

Estimated annual cost of hospital-acquired AKI to US healthcare system

#### 40%[3]

Of ICU patients develop sepsis after AKI diagnosis

#### 10x[5]

Higher mortality rate for inpatient with AKI

\*Data presented are based on published literature and represent general clinical context. They are not specific to FIZE kUO performance

![FIZE kUO device screen showing a urine output curve and flow rate](https://fizemedical.com/wp-content/uploads/2026/03/divicebf-1021x1024.png)

## Altering the therapeutic paradigm to a proactive approach

FIZE Medical’s flagship platform, FIZE kUO, delivers continuous, real-time urine-output data to clinicians, supporting earlier detection of acute kidney injury. By transforming urine output into actionable insight, it enables earlier intervention and improved patient outcomes.

[Learn More](https://fizemedical.com/fize-kuo-adults/)

## The FIZE Medical Vision

## 360° Fluid Management

FIZE Optima™ is a comprehensive software platform designed to optimize the fluid management cycle essential for ICU recovery.

By integrating continuous kidney intelligence with real-time therapeutic guidance, Optima will enable data-backed stabilization and effective decongestion management—targeting a measurable reduction in both clinical complications and the multi-billion dollar burden of ICU length of stay.

## Expert Insights

![Dr. Jacques Braun, Director of the Pediatric ICU at Shaare Zedek Medical Center](https://fizemedical.com/wp-content/uploads/2026/07/ChatGPT-Image-Jul-15-2026-11_03_17-AM-1024x1024.png)

Dr. Jacques Braun
Director of the Pediatric Intensive Care Unit Shaare Zedek Medical Center

“Our experience with the FIZE urine output monitoring system has been very encouraging. It delivers continuous, accurate urine output data, integrates well into the nursing workflow, and provides timely alerts when urine output deviates from expected trends. What stands out to me is that the measurement is taken close to the catheter itself, so the technology is designed to support adults, pediatric, and neonatal patients.”

![Barbara Strain, principal at Barbara Strain Consulting](https://fizemedical.com/wp-content/uploads/2026/03/Layer-14.png)

Barbara Strain
MA, SM (ASCP), CVAHP, is Principal, "Barbara Strain Consulting LLC".

“According to accumulated clinical data, hospital-acquired AKI is caused by various factors.
Despite nurses’ best efforts, it’s hard to optimize every encounter in someone’s hospital stay.
This is why it is highly beneficial to have an accurate detection system, such as the FIZE kUO, supporting early AKI treatment.”

![Dr. Uri Pollak, director of Hadassah Ein Kerem's pediatric ICU](https://fizemedical.com/wp-content/uploads/2025/01/Daniel-Arrelano-1.jpg)

Dr. Uri Pollak
Director of the Pediatric Intensive Care Unit at Hadassah Ein Kerem

In small babies, a 5 cc change will determine if they are anuric, oliguric, or have normal urine output. This precision is crucial for the early detection of AKI, as current manual measurement techniques lack the necessary accuracy to measure such small amounts of urine

![Prof. Moti Klein, Head of Intensive Care at Soroka University Medical Center](https://fizemedical.com/wp-content/uploads/2025/01/Daniel-Arrelano-3.jpg)

Prof. Moti Klein
Head of Intensive Care at Soroka University MC

Automatic, independent, precise, and timely measurement of urine output is crucial for effective monitoring of the critically ill patient. It guides our treatment strategies, informs our interventions, and ultimately impacts patient outcomes

[Read more experts insight](https://fizemedical.com/experts-corner/)

## Our Partners

![Rapha Capital Management logo](https://fizemedical.com/wp-content/uploads/2026/03/Layer-10.png)

![eHealth Ventures logo](https://fizemedical.com/wp-content/uploads/2026/03/Group-32.png)

![Valitas logo](https://fizemedical.com/wp-content/uploads/2026/03/Layer-11.png)

![Neopharm logo](https://fizemedical.com/wp-content/uploads/2026/03/Group-31.png)

## In-Depth Insights:

## Explore Our Articles

[![Doctor typing on a laptop with digital patient record icons overlaid](https://fizemedical.com/wp-content/uploads/2025/04/shutterstock_2601785549-1024x684.jpg)](https://fizemedical.com/article/three-stages-of-acute-kidney-injury/)

[Acute Kidney Injury](https://fizemedical.com/article/three-stages-of-acute-kidney-injury/)

Three Stages of Acute Kidney Injury

[![Prevent Post-Cardiac Surgery AKI](https://fizemedical.com/wp-content/uploads/2025/05/shutterstock_2127970391-1024x546.jpg)](https://fizemedical.com/article/understanding-and-mitigating-acute-kidney-injury-aki-after-cardiac-surgery/)

[AKI and Cardiac Surgery](https://fizemedical.com/article/understanding-and-mitigating-acute-kidney-injury-aki-after-cardiac-surgery/)

Understanding and Mitigating Acute Kidney Injury (AKI) After Cardiac Surgery

[![Fluid Management via Urine Monitoring](https://fizemedical.com/wp-content/uploads/2024/01/Fluid-management-1024x683.jpg)](https://fizemedical.com/article/optimizing-fluid-management-in-critically-ill-patients-the-role-of-continuous-urine-output-monitoring/)

[Fluid Management](https://fizemedical.com/article/optimizing-fluid-management-in-critically-ill-patients-the-role-of-continuous-urine-output-monitoring/)

Optimizing Fluid Management in Critically Ill Patients: The Role of Continuous Urine Output Monitoring

[![Doctor tapping a tablet surrounded by digital health icons](https://fizemedical.com/wp-content/uploads/2025/05/shutterstock_1622205946-1024x590.jpg)](https://fizemedical.com/article/understanding-the-complex-landscape-of-shock-in-critical-care-the-role-of-continuous-urine-output-monitoring/)

[Circulatory Shock](https://fizemedical.com/article/understanding-the-complex-landscape-of-shock-in-critical-care-the-role-of-continuous-urine-output-monitoring/)

Understanding the Complex Landscape of Shock in Critical Care: The Role of Continuous Urine Output Monitoring

## News & Events

## [New Peer-Reviewed Study Explores Continuous Kidney UO Data in ICU Fluid Management](https://fizemedical.com/events/new-peer-reviewed-study-explores-continuous-kidney-uo-data-in-icu-fluid-management/)

 12.10.2026

## [FIZE Medical Featured in Calcalist Tech](https://fizemedical.com/other-news/fize-medical-featured-in-calcalist-tech/)

 18.09.2026

## [FIZE Medical Announces First Close of 20$ Series B Financing Co-Led by Asahi Kasei Medical and Rapha Capital](https://fizemedical.com/news/fize-medical-announces-first-close-of-20-series-b-financing-co-led-by-asahi-kasei-medical-and-rapha-capital/)

 17.09.2026

## [FIZE Medical is pleased to announce it has received CE Mark and UKCA Certification for its FIZE kUO® System.](https://fizemedical.com/other-news/fize-medical-is-pleased-to-announce-it-has-received-ce-mark-and-ukca-certification-for-its-fize-kuo-system/)

 27.07.2026

[See all](https://fizemedical.com/news/)

**1** [Minor et al., Scientific Reports, 2021](https://www.nature.com/articles/s41598-021-97026-8) **2** [CDC FastStats — Leading Causes of Death](http://www.cdc.gov/nchs/fastats/leading-causes-of-death.htm)
**3**  [Trotter et al., *BMJ Quality Improvement Reports,* 2014](http://pubmed.ncbi.nlm.nih.gov/26734260/)
**4**  [Chertow et al.,*JASN,* 2005](http://pubmed.ncbi.nlm.nih.gov/16177006/)
**5**  [Dasta et al., *Nephrology Dialysis Transplantation* , 2008](https://pubmed.ncbi.nlm.nih.gov/18178605/)
